Nikon Confocal Microscope System AX / AX R

Improving on Perfection

Our 10th generation point scanning confocal
- Leveraging Artificial Intelligence (AI)
- Expanding the number of colors
- Improving pixel density
- Sensitivity and speed.

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Ultra Large Field of View

With the largest field-of-view on both inverted and upright microscope stands available (25mm diagonal), more specimens fit in one FOV with more objective lens choices than ever before.

Coupled with scanning sizes up to 8192 x 8192 pixels, sampling beyond the optical diffraction limit is possible even at low magnifications with the AX/AX R.

Using lower magnifications with longer working distances and high numerical apertures enables more flexible specimen preparations to be used, while the large FOV allows simultaneous high resolution in one image. Collect more data in every image, and at faster rates.

High Speed Resonant Scanning

The AX R’s high speed resonant scanning, which decreases the illumination time by more than 20x typical confocal scanning times, greatly reduces biases caused by merely acquiring images. Reducing the acquisition time also allows for extremely high-speed imaging (up to 720 fps @ 2048 x 16).

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High Resolution

With a full 25mm FOV, up to 8192 x 8192 pixels, and the capability for supravideo frame rates, the AX/AX R allows for spectacular imaging with high resolution, at both low and high magnifications.

The entire range of a whole organism or system biology down to intracellular imaging is achievable on one instrument.

AI Software

Autosignal.ai
adjust to the best illumination and detection settings automatically

Denoise.ai
Remove the shot noise component, improve the image quality, and assist in downstream segmentation

Segment.ai 
By tracing features of interest and training these compared to the underlying image, the neural network can learn and apply segmentation to similar images, recognizing features previously only identifiable by painstaking manual tracing approaches.

*Photos and Videos courtesy of Nikon official website

NSPARC

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AX Confocal with NSPARC

Extent the Imaging Potential

Low noise Nikon Spatial Array Confocal (NSPARC) detector, resulting in high sensitivity, high signal-to-noise, and possibility of live-cell assay.

High Content Imaging

Intelligent Acquisition System

With Nikon microscope and software NIS-Elements, our high content imaging streamlines high-speed imaging and simple operations. Nikon software provides a dedicated interface for high content acquisition and analysis routines.

Without the need to adjust the focusing method, wavelengths, filters, and camera settings, it is easier to process alongside your research quickly and effortlessly. 

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Applications

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High Content Imaging

A study of living cells using microscopy to obtain a better understanding of biological function through the study of cellular dynamics.

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Fluorescence

Fluorescence itself is a form of luminescence that results from matter emitting light of a certain wavelength after absorbing electromagnetic radiation. Fluorescence Imaging help visualize biological processes taking place in a living organism.

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Neurobiology / Optogenetics

Is the study of the nervous system. The scope of neuroscience has broadened over time to include different approaches, such as optogenetics, a biological technique to control the activity of neurons or other cell types with light. This is achieved by the expression of light-sensitive ion channels, pumps, or enzymes specifically in the target cells.

Related Products

Microscopes

Nikon Inverted Microscope
Ti2-E
Nikon Spinning Disk Confocal
Nikon Super Resolution N-SIM
Nikon Super Resolution N-STORM

Software

Nikon NIS-Elements
High Content Analysis HC
Nikon NIS-Elements C
Nikon NIS-Elements AR

LED Light Source for Fluorescence

Nikon LED Light Source for Fluorescence
D-LEDI
About

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