Molecular Devices
Electrophysiology instruments

Cellular Imaging

Powerful tools for high content screening and research imaging analysis.

Electrophysiology

Electrophysiology Automated and conventional voltage clamp instruments for drug discovery.

Fluorometric Imaging Readers

Cell-based benchtop and high-throughput screening systems with fluidics.

Liquid Handling

Automated washer/dispenser system, cell- and well-washers, cell harvesters.

Microarray Analysis & LCM

Microarray scanners, image analysis and microarray informatics software.

Laser Capture Microdissection Systems

Microplate Readers

Single- and multi-mode microplate readers with SoftMax Pro software.

Conventional Electrophysiology

Microelectrode Amplifiers

Axoclamp 900A is a computer-controlled microelectrode current-clamp and voltage-clamp amplifier, useful for a wide range of intracellular microelectrode recording techniques with several modes of operation: two independent current clamp amplifiers with bridge balance, two-electrode voltage clamp, discontinuous current clamp, discontinuous single-electrode voltage clamp, and high-voltage current clamp.

MultiClamp 700B

MultiClamp 700B is a computer-controlled microelectrode amplifier with a high-speed current clamp capable of sharp-electrode, field potential or ion-selective measurements, and a patch clamp for whole-cell, excised or cell-attached patches, bilayers, and electrochemistry with voltammetry or amperometry.

Axopatch 200B

Axopatch 200B is the premier patch-clamp amplifier for all patch-clamp configurations, with capacitive-feedback and cooling in the headstage for ultra-low noise single-channel recordings.

Data Acquisition Systems

Digidata 1440A is a low-noise digitizer for recording data onto a Windows computer. Digidata 1440A is compatible with pCLAMP 10.

Digidata 1440A

Electroporation

Axoporator 800A is the world's first commercially available micropipette-based system for single-cell electroporation.

Axoporator 800A

Burleigh® PCS-5000

Ultimate Control in Manual Manipulation

The Burleigh® PCS-6000 Piezoelectric micromanipulator system combines ease of use with ultra-precise positioning to achieve the best possible results with the highest productivity. Its long travel motors give flexibility for coarse positioning, and Piezoelectric technology provides extremely smooth, very precise movement for the final patch.

Burleigh® PCS-6000

Our Most Advanced, Motorized Micropositioning Technology

Burleigh® Gibraltar®

The Most Dependable Mounting Solution For Fixed-Stage, Upright Microscopes

The Burleigh® Gibraltar® Platform and X-Y stage provide outstanding motorized hands-free movement for fixed-stage upright microscopes. The microscope can be moved smoothly and precisely between fields of view without disturbing an established patch, while the motorized translation stage ensures that you never lose a position of interest.

Perfusion Systems

4-channel Valve Controller

The VC3-4 Valve Commander is a low cost valve control system for bath, tissue, cell, and Oocyte perfusion. Combine the VC3 controller with the various pressure driven valve manifolds to simplify the addition of solutions to your experiemnt.

8-channel Valve Control System

Perfusion is critical in most biological applications, both for maintaining the viability of preparations and establishing experimental conditions. Electronic control of solution exchange improves fluid delivery and enhances reproducibility over manual methods. With the VC3-8 systems, you can configure systems for the basic requirements of the student lab or you can optimize them for the most demanding applications of patch-clamp recording and / or imaging.

OctaFlow

The new OctaFlowTM is ALA's latest instrument for rapid, accurate and programmable superfusion of solutions onto dissociated cells or tissue slices. The OctaFlowTM controls up to 32 valves in 4 valve banks of 8 valves each. It can be upgraded inexpensively from single bank (8 valves) to 4 bank (32 valves) systems. The system delivers solutions through ALA's proprietary QMM MicromanifoldTM the device chosen by hundreds of academic and industrial labs for the most demanding drug delivery applications.

High Speed Pressure Clamp

Mechanosensitive ion channel Pressure Clamp System

The HSPC-1 is the only commercially available device for executing pressure-clamp protocols for studying mechanosensitive channel gating. It is entirely compatible with existing patch amplifiers, headstages and electrodes holders, and delivers pre-programmed pressure changes to cells during conventional voltage-clamp recording in the whole-cell configuration.

Micromanipulators

Motorized, Base Mount 4 Axis

The MX7600 motorized 4-axis micromanipulator is ideal for patch and intracellular recording experiments. Crossed-roller bearings provide exceptionally smooth linear travel. Precision preloaded lead screws with encoded, closed-loop DC motors ensure drift-free operation. The probe axis is independent, with a clamp that allows angular adjustment from 0° to 180° - you aren't limited to pre-programmed angles. The electrode travels straight into the target cell, not by iterating between two axes with a " stair-step " approach created by a " synthetic " 4th axis.

Siskiyou - MX7600