BioPrecision2 stages are designed for demanding applications where speed, repeatability and accuracy are required. These stages utilize precision ground crossed roller bearing guideways, recirculating ball leadscrews, and precision motors. All components used in these stages are machined with state of the art CNC equipment resulting in the highest stage performance. All stage components are black anodized for durability and long lasting appearance. A full compliment of specimen holder inserts are available for almost any application including single slides, double slides and petri dishes. Custom holders are available.

The LEP filter wheel provides fast, automated and efficient optical filter changing for microscopes. The filter wheel position is digitally encoded which makes it immune to slippage and skipping errors. Filter positioning errors affect the performance of the micrsocope and add uneccessary variations to the measurement results. The wheel is driven by a DC servo specifically selected for smooth, quiet, damped wheel motion. The LEP filter wheels utilize the MAC 5000 controller system. The MAC 5000 provides high performance and flexibility and is supported with almost any available imaging software application. The filter wheel is designed to be robust and accurate.

The BioPrecision focus control system provides accurate, high resolution automated control of the microscope focus. The basic focus control system consists of a high resolution stepper motor that is coupled to the microscope focus drive. The MAC 5000 automation controller tracks position and provides for manual control through the use of the 73000365 digipot control. A high resolution linear encoder option is available to provide feedback of the actual focus height (not just the focus knob position). The Z-axis linear encoder device has resolution of 50nm, with measurement range of 12mm.

 

Warm, filtered air circulates within an acrylic enclosure from a heater unit which is mechanically isolated from the environmental chamber. Users may select temperatures within the range 32oC* to 42oC.

The specimen, being at the centre of the enclosure, is uniformly heated. It receives heat in X,Y and Z planes. Access to change specimens is provided through doors designed for both left and right handed researchers. Adjustments to the condenser and nosepiece are also made through these access ports whilst the regular controls of the microscope, e.g. focus and stage movement remain outside the enclosure. Accessories such as cameras, filter wheels, monochromators, micromanipulators, and multi-viewing heads can be accommodated.

The full enclosure incubation chamber provides a heated environment all around the specimen. The stage, nosepiece and a large part of the microscope frame are at physiological temperature. There is no need for supplementary objective and/or stage heaters.

Keeping the live cells under a humid 5% CO2 atmosphere maintains the pH of the growth medium. Humidity does not need to be ‘controlled’. It simply needs to be maintained close to the saturated vapour pressure of water at 37oC. Under these conditions evaporation is prevented and the cells remain stress free. The flow rate of the blanketing gas is low so there is little need for creating the CO2/air mixture in situ. It is more economical to use premixed 5% CO2 in air from a laboratory gas cylinder. In the case of Upright Microscopes, CO2 atmosphere control is possible when dipping objectives are used.

Maintaining living cells in the dark can further help to keep them stress free. In multi-photon microscopy the observed signal is very weak. The background noise from the detectors is significant so the signal to noise ratio is a matter of serious consideration. Current technology indicates that there is little that can be done to enhance the signal strength, but if the background noise is reduced by lowering the ambient light level, there is a significant increase in the signal to noise ratio. A low light level enclosure means that good experimental data can be obtained under red light conditions.

INU Series provides optimal culture environment for steady time-lapse, short/long term imaging with confocal, fluorescence, phase contrast, differential interference contrast and polarization applications. Major Applications: Short/long-term time-lapse and live cell imaging of signal transduction, formation, behavior, migration, propagation and differentiation during cell/tissue/organ culture under microscope in stem cell research, Cell/Molecular Biology, Biochemistry, Neuroscience, and in other research fields that require environment control.

THERMOPLATER is an optical clear glass heating device that provides consistent temperature control of specimen from directly beneath during microscopic observation. Wide product range supports almost all microscopes. Major Applications: Temperature control of specimens in the fields of IVF, stem cell research, Cell/Molecular Biology, Biochemistry, Electrical-Physiology and other research fields.

Properly conditioned gas is supplied during Live Cell Imaging Making stable 5% CO2+ 95% Air mixed gas supply from 100% CO2 possible. Major Applications: Stable CO2 mixed Gas supply during live cell culture in Stage Top Incubator INU Series.

Chamlide TC

Incubator system for various types of chambers

- Chamlide TC can be used on almost any microscope stage (Depending on the stage type, the Chamlide TC requires an incubator holder). The Chamlide TC was originally designed to fit stages with the universal mounting frame K standard stages or most XY-motorized stages.

- Chamlide TC can accept both various Chamlide magnetic chambers and commercial culture dishes using 5 types of adaptors.

- Chamlide TC includes special glass covers for disposable culture wares to maintain humidity and provide excellent transmission for imaging. (For Lab-Tek chambered coverglass, chambered slide, and 35mm culutre dish)

- The controller (CU-109) controls temperatures of the incubator main body, incubator cover, humidifier, and lens warmer, as well as adjust the flow rate of the mixed CO2 gas by using the flow meter (less than 100 ml/min).

- The FC-5 or FC-7 can provide optimum mixed gas to all incubator systems such as Chamlide TC, WP, and IC.

- Chamlide TC is available with in/out ports for perfusion or injection of liquids or drugs without having to open the incubator cover(using CM-B-PA, CM-B-PB).

- It is possible to control the temperature and gas concentration, program temperature and gas concentration gradients, and record the temperature and gas concentration over time using CCP ver 3.8 software or MetaMorph software.

Adaptors available

- TC adaptor for Chambered coverglass

: Nunc Lab-Tek™ II Chambered Coverglass (consumable, coverslip bottom)

- TC adaptor for 2-hole type Chamlide MB or Well-Slide/ Well-slip

: Chamlide MB(Chamlide magnetic chamber s), re-useable, coverslip bottom) , Well-Slide (re-useable, slide glass bottom), or Well-Slip (re-useable, coverslip bottom)

- TC adaptor for 35 mm dish type chamber or dish

: Commercial 35mm culture dishes (consumable) or 35mm dish type Chamlide magnetic chambers (re-useable)

- TC adaptor for Chamber Slide

: Nunc Lab-Tek™ II Chamber Slides (consumable,slide glass bottom)

ASI Piezo Z-stage:

Specifications

MRC Ltd., founded since 1989, is Israel's most innovative supplier of laboratory equipments. MRC’s products including Autoclave, Balances, Baths, Centrifuge, Data loggers, Dry Cabinets, Electrophoresis, Meters, Vacuum and other general equipments.

Vibration Isolation Specialist

"VISOLATOR" is a vibration isolation system which makes the isolation for this type of vibration become a reality. (*VISOLATOR is our company's registered trademark)

As a professional maker of vibration isolation system (VIOSLATOR) for protecting precision instruments from harmful vibration, MEIRITSU SEIKI Co., Ltd. has developed the first full-scale vibration isolation system in Japan. Since then, a lot of vibration isolation systems (ranging from desktop-type to large-scale-table-type used for optical experiments etc.) have been delivered to market by leveraging our technology & know-how gaining from long experience in this field and feedback solutions by detail observations of various optical experiments.

Major Applications

Scanning Microscope, Laser Microscope, Optical Microscope, Microscope for Bio-Medical Applications, Microscope for Industrial Applications, IC Inspection Microscope, Surface Configuration Measurement Meter, Microscope for LCD Manufacturing & Inspection Applications, Electrical Physiology Experiment, Microscope Fertilization Experiment, Manipulator, Microtome

 

Offers anti-vibration tables, desktop air suspension boards and more -